User's Manual

The Prokaryotic Sequence homology Analysis Tool (PSAT) is a public web based tool designed to help researchers utilize sequence homology results (from protein BLAST) for various comparative genomics tasks. PSAT utilizes a database of precalculated homology data, including special processing of BLAST results to help identify conserved order of homologs between genomes. PSAT's interface was designed to enable researchers to quickly and intuitively visualize these homology data for different types of analyses. The tool can help identify gene orthologs, suggest loss of function within genomes, find potential functional clusters of genes among multiple genomes, or visualize potential gene deletions or inversions.

Demonstrations of how PSAT can be utilized for these various tasks can be found in the Examples section below. For details on performing the different types of analyses available in our tool, take the tutorial, or jump to the relevant section from the table of contents.